Rett syndrome primarily affects which gender, according to the material?

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Multiple Choice

Rett syndrome primarily affects which gender, according to the material?

Explanation:
Rett syndrome is an X-linked dominant neurodevelopmental disorder, most often caused by MECP2 mutations. In males, the mutation tends to cause severe illness or early death, while females survive due to X-inactivation causing mosaic expression, leading to the characteristic Rett features. This results in a pattern where the condition primarily affects girls. Rarely, affected boys can occur in unusual genetic contexts, but the material emphasizes girls as the primary group.

Rett syndrome is an X-linked dominant neurodevelopmental disorder, most often caused by MECP2 mutations. In males, the mutation tends to cause severe illness or early death, while females survive due to X-inactivation causing mosaic expression, leading to the characteristic Rett features. This results in a pattern where the condition primarily affects girls. Rarely, affected boys can occur in unusual genetic contexts, but the material emphasizes girls as the primary group.

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